Physician-guided pain care & longevity medicineMount Dora & Land O’ Lakes, Florida
DR. TODD MAUTNER, DOBoard-Certified Anesthesiologist Fellowship-Trained Pain Specialist
352-744-8017
Investigational / not FDA-approved for chronic pain
A MORE THOUGHTFUL APPROACH

Wharton’s Jelly: Perinatal Tissue Research

Understanding umbilical-cord connective tissue and investigational clinical uses.

Wharton’s jelly is a gelatinous connective tissue within the umbilical cord. It contains structural extracellular-matrix components and can be a source of cells in research settings. Acellular tissue preparations and living-cell products are not interchangeable.

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✓ Physician-guided✓ Informed decisions✓ Central Florida
Florida statutory stem-cell notice · §459.0127

THIS NOTICE MUST BE PROVIDED TO YOU UNDER FLORIDA LAW. This physician performs one or more stem cell therapies that have not yet been approved by the United States Food and Drug Administration. You are encouraged to consult with your primary care provider before undergoing any stem cell therapy.

This statutory notice does not itself establish FDA authorization or that any particular product or procedure can lawfully be administered.

01

A tissue, not a standardized therapy

Products described as Wharton’s jelly may contain different amounts of extracellular matrix, cellular material or processed components. Processing can change their composition and regulatory classification.

02

What researchers are investigating

Investigations examine tissue scaffolding properties, cell behavior and possible roles in tissue-related research. Claims that Wharton’s jelly injections rebuild cartilage, heal discs or eliminate chronic pain are not established in humans.

03

What patients should know

FDA has not approved Wharton’s jelly products for osteoarthritis, spinal disease, chronic pain or other orthopedic conditions. Injection and implantation may pose infection, immune-response and other risks. Use for a specific indication may require FDA authorization.

04

Regulation and ethical sourcing

Source, donor screening, manufacturing, intended use and applicable FDA requirements all matter. Florida has additional requirements for some stem-cell-related services; state provisions do not displace federal law.

Answers & context

Frequently asked questions

Is Wharton’s jelly the same as MSCs?+
No. The tissue contains matrix and may be a source of MSC-like cells, but the products are distinct.
Does it regrow cartilage?+
Cartilage-regeneration claims for injected Wharton’s jelly are not established by adequate human evidence.
Is it FDA-approved for joint pain?+
No FDA-approved Wharton’s jelly product treats joint pain or osteoarthritis.
Discover more

Continue exploring

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01 / RESEARCH

Mesenchymal Stromal Cells (MSCs)

What is known—and unknown—about multipotent stromal-cell research.

02 / RESEARCH

Exosomes: Cellular Communication

Exploring an emerging area of regenerative medicine science—not an established pain treatment.

03 / RESEARCH

MUSE Cells: An Emerging Research Field

Multilineage-differentiating stress-enduring cells and the questions researchers are asking.

04 / EXPLORE

Regulatory & Patient Safety Information

What FDA authorization, evidence, research oversight and informed consent really mean.

We’re here to help

Have questions about the research?

Our team can explain the scientific and regulatory context. This does not represent an offer of investigational treatment.